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Liquid Biopsy

It’s an aspirational goal: develop a simple blood test that can detect cancer cells in an asymptomatic patient, locate the tissue of origin, and give that person an early diagnosis when treatment is more likely to be successful. This is the promise of liquid biopsy, a technology that can capture cell-free DNA (cfDNA), circulating tumor DNA (ctDNA) and even whole—sometimes live—circulating tumor cells (CTCs) from a simple blood draw and analyze them either via PCR or next-generation sequencing to derive virtually the same information one could from a tumor tissue sample.

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