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Customised Flow Cytometry Solutions (ICON)

ICON’s R&D and Operational teams have the resources and scientific expertise to implement a broad range of custom flow cytometric assays in clinical trials. Custom flow cytometric assays are validated using a fit-for-purpose approach with the level of assay characterization consistent with the intended use of the assay results. Moreover, an experienced R&D scientific team develops and validates complex flow cytometric assays and trains dedicated Operational staff to perform ongoing clinical trial sample processing and analysis using standardized SOPs and data analysis strategies. Our global flow cytometry network has laboratory locations in New York, Dublin and Singapore, and all instruments are connected to a central flow cytometry server. Having a central server allows us to utilize fully harmonized and standardized processes and instrumentation for even the most complex assays.

ICON Central Laboratories

123 Smith Street
Farmingdale, NY 11735

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  • Receptor occupancy assays, customized per drug
  • Antibody-dependent cell-mediated cytotoxicity assays
  • Rare event enumeration and ultra-rare event enumeration
  • T cell maturation phases (naďve, central memory, effector memory)
  • B cell maturation phases (naďve, switched memory, unswitched memory, double negative)
  • In vitro stimulation and quantification of intracellular cytokines
  • Phosphorylation, basophil, eosinophil assays
  • Microbead-based enrichment of T lymphocytes, B lymphocytes, granulocytes, monocytes and disease-state immune cells
  • Custom RUO flow cytometric assay approved by New York State Department of Health for use as a clinical diagnostic assay to support patient enrollment
  • Flow cytometric assays to support companion diagnostics

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Customised Flow Cytometry Solutions

Customised Flow Cytometry Solutions (ICON)

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