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Synthetic Matrix II HD917 (Horizon)

The most flexible whole process reference standard for cfDNA recovery.

Optimal synthetic matrix enables extraction recovery of cfDNA by multiple purification methods. Clinically-relevant mutations in an artificial matrix give you full control of your cfDNA workflow, reducing the likelihood of a false negative or positive due to incorrect assay loading. Multiplex I cfDNA Reference Standard Set in Synthetic Matrix II contains 8 onco-relevant mutations to measure your extraction efficiency.

The Multiplex I cfDNA Reference Standard Set in Synthetic matrix II covers multiple engineered single nucleotide variants (SNVs/SNPs) with 8 mutations at 5%, 1%, and 0.1% allelic frequencies.

For information on specific gene copies detected in each product batch, download the Certificate of Analysis from the resources tab.


Horizon Discovery Ltd.

Building 8100
Cambridge Research Park,
Waterbeach, Cambridge, CB25 9TL
United Kingdom
800-235-9880
www.horizondiscovery.com

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Technical data

  • Format: cfDNA
  • Genes covered: EGFR, KRAS, NRAS, PIK3CA
  • Cosmics: 1,500+
  • Allelic frequencies: 5%, 1%, 0.1% and 0% (100% wild type)
  • Buffer: Synthetic matrix II
  • Expected DNA yield: ≥120 ng DNA per mL of product using the QIAamp® Circulating Nucleic Acid Kit with 2 mL extraction input

Product information

  • Fragment size: 170bp
  • Unit size: 400ng per 1ml (4 vials total)

POSTERS & PAPERS

Article: Controlling variabilities in liquid biopsy

Synthetic Matrix II HD917 (Horizon)

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